Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer’s Disease progression

Despite a key role of amyloid-beta (Aβ) in Alzheimer’s disease (AD), mechanisms that link Aβ plaques to tau neurofibrillary tangles and cognitive decline still remain poorly understood. The purpose of this study was to quantify proteins in the sarkosyl-insoluble brain proteome correlated with Aβ and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proteomics
Päätekijät: Hales, Chadwick M., Dammer, Eric B., Deng, Qiudong, Duong, Duc M., Gearing, Marla, Troncoso, Juan C., Thambisetty, Madhav, Lah, James J., Shulman, Joshua M., Levey, Allan I., Seyfried, Nicholas T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462625/
https://ncbi.nlm.nih.gov/pubmed/27718298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201600057
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