Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer’s Disease progression

Despite a key role of amyloid-beta (Aβ) in Alzheimer’s disease (AD), mechanisms that link Aβ plaques to tau neurofibrillary tangles and cognitive decline still remain poorly understood. The purpose of this study was to quantify proteins in the sarkosyl-insoluble brain proteome correlated with Aβ and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proteomics
Egile Nagusiak: Hales, Chadwick M., Dammer, Eric B., Deng, Qiudong, Duong, Duc M., Gearing, Marla, Troncoso, Juan C., Thambisetty, Madhav, Lah, James J., Shulman, Joshua M., Levey, Allan I., Seyfried, Nicholas T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462625/
https://ncbi.nlm.nih.gov/pubmed/27718298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201600057
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