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Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer’s disease

Neurodegenerative diseases are often defined pathologically by the presence of protein aggregates. These aggregates, including amyloid plaques in Alzheimer’s disease (AD), result from the abnormal accumulation and processing of proteins, and may ultimately lead to neuronal dysfunction and cell death...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gozal, Yair M., Duong, Duc M., Gearing, Marla, Cheng, Dongmei, Hanfelt, John J., Funderburk, Christopher, Peng, Junmin, Lah, James J., Levey, Allan I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784247/
https://ncbi.nlm.nih.gov/pubmed/19746990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr900474t
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