Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards

A hallmark of neurodegeneration is the aggregation of disease related proteins that are resistant to detergent extraction. In the major pathological subtype of frontotemporal lobar degeneration (FTLD), modified TAR-DNA binding protein 43 (TDP-43), including phosphorylated, ubiquitinated and proteoly...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Seyfried, Nicholas T., Gozal, Yair M., Donovan, Laura E., Herskowitz, Jeremy H., Dammer, Eric B., Xia, Qiangwei, Ku, Li, Chang, Jianjun, Duong, Duc M., Rees, Howard D., Cooper, Deborah S., Glass, Jonathan D., Gearing, Marla, Tansey, Malú G., Lah, James J., Feng, Yue, Levey, Allan I., Peng, Junmin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357000/
https://ncbi.nlm.nih.gov/pubmed/22416763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr2010814
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi