U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease

Deposition of insoluble protein aggregates is a hallmark of neurodegenerative diseases. The universal presence of β-amyloid and tau in Alzheimer’s disease (AD) has facilitated advancement of the amyloid cascade and tau hypotheses that have dominated AD pathogenesis research and therapeutic developme...

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Autors principals: Bai, Bing, Hales, Chadwick M., Chen, Ping-Chung, Gozal, Yair, Dammer, Eric B., Fritz, Jason J., Wang, Xusheng, Xia, Qiangwei, Duong, Duc M., Street, Craig, Cantero, Gloria, Cheng, Dongmei, Jones, Drew R., Wu, Zhiping, Li, Yuxin, Diner, Ian, Heilman, Craig J., Rees, Howard D., Wu, Hao, Lin, Li, Szulwach, Keith E., Gearing, Marla, Mufson, Elliott J., Bennett, David A., Montine, Thomas J., Seyfried, Nicholas T., Wingo, Thomas S., Sun, Yi E., Jin, Peng, Hanfelt, John, Willcock, Donna M., Levey, Allan, Lah, James J., Peng, Junmin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799305/
https://ncbi.nlm.nih.gov/pubmed/24023061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310249110
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