U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease

Deposition of insoluble protein aggregates is a hallmark of neurodegenerative diseases. The universal presence of β-amyloid and tau in Alzheimer’s disease (AD) has facilitated advancement of the amyloid cascade and tau hypotheses that have dominated AD pathogenesis research and therapeutic developme...

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Detalhes bibliográficos
Main Authors: Bai, Bing, Hales, Chadwick M., Chen, Ping-Chung, Gozal, Yair, Dammer, Eric B., Fritz, Jason J., Wang, Xusheng, Xia, Qiangwei, Duong, Duc M., Street, Craig, Cantero, Gloria, Cheng, Dongmei, Jones, Drew R., Wu, Zhiping, Li, Yuxin, Diner, Ian, Heilman, Craig J., Rees, Howard D., Wu, Hao, Lin, Li, Szulwach, Keith E., Gearing, Marla, Mufson, Elliott J., Bennett, David A., Montine, Thomas J., Seyfried, Nicholas T., Wingo, Thomas S., Sun, Yi E., Jin, Peng, Hanfelt, John, Willcock, Donna M., Levey, Allan, Lah, James J., Peng, Junmin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799305/
https://ncbi.nlm.nih.gov/pubmed/24023061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310249110
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