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Asparaginyl endopeptidase cleaves TDP-43 in brain
TAR DNA-binding protein 43 (TDP-43) is a nuclear protein involved in RNA splicing and a major protein component in ubiquitin-positive, tau-negative inclusions of frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). Under disease conditions TDP-43 redistributes to the cyt...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3787696/ https://ncbi.nlm.nih.gov/pubmed/22718532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201200006 |
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