Mechanism of ceroid formation in atherosclerotic plaque: in situ studies using a combination of Raman and fluorescence spectroscopy

di Haka, Abigail S., Kramer, John R., Dasari, Ramachandra R., Fitzmaurice, Maryann
Pubblicazione 2011

Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low density lipoprotein

di Haka, Abigail S., Grosheva, Inna, Singh, Rajesh K., Maxfield, Frederick R.
Pubblicazione 2013

High-density lipoprotein or cyclodextrin extraction of cholesterol from aggregated LDL reduces foam cell formation

di Singh, Rajesh K., Lund, Frederik W., Haka, Abigail S., Maxfield, Frederick R.
Pubblicato in J Cell Sci (2019)

Aggregated LDL in contact with macrophages induces local increases in free cholesterol levels that regulate local actin polymerization

di Grosheva, Inna, Haka, Abigail S., Qin, Chunbo, Pierini, Lynda M., Maxfield, Frederick R.
Pubblicazione 2009

Quantitative Analysis of Monocyte Subpopulations in Murine Atherosclerotic Plaques by Multiphoton Microscopy

di Haka, Abigail S., Potteaux, Stephane, Fraser, Haley, Randolph, Gwendalyn J., Maxfield, Frederick R.
Pubblicazione 2012

Dynamic Actin Reorganization and Vav/Cdc42-dependent Actin Polymerization Promote Macrophage Aggregated LDL Uptake and Catabolism

di Singh, Rajesh K., Haka, Abigail S., Bhardwaj, Priya, Zha, Xiaohui, Maxfield, Frederick R.
Pubblicato in Arterioscler Thromb Vasc Biol (2019)

Diagnosing breast cancer by using Raman spectroscopy

di Haka, Abigail S., Shafer-Peltier, Karen E., Fitzmaurice, Maryann, Crowe, Joseph, Dasari, Ramachandra R., Feld, Michael S.
Pubblicazione 2005

Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse

di Singh, Rajesh K., Barbosa-Lorenzi, Valéria C., Lund, Frederik W., Grosheva, Inna, Maxfield, Frederick R., Haka, Abigail S.
Pubblicato in J Cell Sci (2016)

Macrophages Create an Acidic Extracellular Hydrolytic Compartment to Digest Aggregated Lipoproteins

di Haka, Abigail S., Grosheva, Inna, Chiang, Ethan, Buxbaum, Adina R., Baird, Barbara A., Pierini, Lynda M., Maxfield, Frederick R.
Pubblicazione 2009

Diagnosing breast cancer using Raman spectroscopy: prospective analysis

di Haka, Abigail S., Volynskaya, Zoya, Gardecki, Joseph A., Nazemi, Jon, Shenk, Robert, Wang, Nancy, Dasari, Ramachandra R., Fitzmaurice, Maryann, Feld, Michael S.
Pubblicazione 2009

Monocyte-derived dendritic cells upregulate extracellular catabolism of aggregated LDL upon maturation, leading to foam cell formation

di Haka, Abigail S., Singh, Rajesh K., Grosheva, Inna, Hoffner, Haley, Capetillo-Zarate, Estibaliz, Chin, Harvey F., Anandasabapathy, Niroshana, Maxfield, Frederick R.
Pubblicato in Arterioscler Thromb Vasc Biol (2015)

Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation

di Haka, Abigail S., Barbosa-Lorenzi, Valéria C., Lee, Hyuek Jong, Falcone, Domenick J., Hudis, Clifford A., Dannenberg, Andrew J., Maxfield, Frederick R.
Pubblicato in J Lipid Res (2016)

Ceramide activation of RhoA/Rho kinase impairs actin polymerization during aggregated LDL catabolism

di Singh, Rajesh K., Haka, Abigail S., Brumfield, Alexandria, Grosheva, Inna, Bhardwaj, Priya, Chin, Harvey F., Xiong, Yuquan, Hla, Timothy, Maxfield, Frederick R.
Pubblicato in J Lipid Res (2017)

TLR4-dependent signaling drives extracellular catabolism of low-density lipoprotein aggregates

di Singh, Rajesh K., Haka, Abigail S., Asmal, Arky, Barbosa-Lorenzi, Valéria C., Grosheva, Inna, Chin, Harvey F., Xiong, Yuquan, Hla, Timothy, Maxfield, Frederick R.
Pubblicato in Arterioscler Thromb Vasc Biol (2019)

Sphingosine Kinases Are Not Required for Inflammatory Responses in Macrophages

di Xiong, Yuquan, Lee, Hyeuk Jong, Mariko, Boubacar, Lu, Yi-Chien, Dannenberg, Andrew J., Haka, Abigail S., Maxfield, Frederick R., Camerer, Eric, Proia, Richard L., Hla, Timothy
Pubblicazione 2013

Sphingosine kinases are not required for inflammatory responses in macrophages.

di Xiong, Yuquan, Lee, Hyuek Jong, Mariko, Boubacar, Lu, Yi-Chien, Dannenberg, Andrew J., Haka, Abigail S., Maxfield, Frederick R., Camerer, Eric, Proia, Richard L., Hla, Timothy
Pubblicato in J Biol Chem (2016)

Detection of Coronary Atherosclerotic Plaques with Superficial Proteoglycans and Foam Cells using Real-Time Intrinsic Fluorescence Spectroscopy

di Angheloiu, George O., Haka, Abigail S., Georgakoudi, Irene, Arendt, Joseph, Müller, Markus G., Scepanovic, Obrad R., Evanko, Stephen P., Wight, Thomas N., Mukherjee, Prasun, Waldeck, David H., Dasari, Ramachandra R., Fitzmaurice, Maryann, Kramer, John R., Feld, Michael S.
Pubblicazione 2010

A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux

di Jena, Prakrit V., Roxbury, Daniel, Galassi, Thomas V., Akkari, Leila, Horoszko, Christopher P., Iaea, David B., Budhathoki-Uprety, Januka, Pipalia, Nina, Haka, Abigail S., Harvey, Jackson D., Mittal, Jeetain, Maxfield, Frederick R., Joyce, Johanna A., Heller, Daniel A.
Pubblicato in ACS Nano (2017)

Metabolically activated adipose tissue macrophages perform detrimental and beneficial functions during diet-induced obesity

di Coats, Brittney R., Schoenfelt, Kelly Q., Barbosa-Lorenzi, Valéria C., Peris, Eduard, Cui, Chang, Hoffman, Alexandria, Zhou, Guolin, Fernandez, Sully, Zhai, Lijie, Hall, Ben A., Haka, Abigail S., Shah, Ajay M., Reardon, Catherine A., Brady, Matthew J., Rhodes, Christopher, Maxfield, Frederick R., Becker, Lev
Pubblicato in Cell Rep (2017)

Optimization of 1,2,5-Thiadiazole Carbamates as Potent and Selective ABHD6 Inhibitors ()

di Patel, Jayendra Z., Nevalainen, Tapio J., Savinainen, Juha R., Adams, Yahaya, Laitinen, Tuomo, Runyon, Robert S., Vaara, Miia, Ahenkorah, Stephen, Kaczor, Agnieszka A., Navia-Paldanius, Dina, Gynther, Mikko, Aaltonen, Niina, Joharapurkar, Amit A., Jain, Mukul R., Haka, Abigail S., Maxfield, Frederick R., Laitinen, Jarmo T., Parkkari, Teija
Pubblicato in ChemMedChem (2014)