Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

Por Navia-Paldanius, Dina, Savinainen, Juha R., Laitinen, Jarmo T.
Publicado em 2012

Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes

Por Savinainen, Juha R, Järvinen, Tomi, Laine, Krista, Laitinen, Jarmo T
Publicado em 2001

S-Nitrosothiols modulate G protein-coupled receptor signaling in a reversible and highly receptor-specific manner

Por Kokkola, Tarja, Savinainen, Juha R, Mönkkönen, Kati S, Retamal, Montse Durán, Laitinen, Jarmo T
Publicado em 2005

An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A(1) and cannabinoid CB(1) receptors

Por Savinainen, Juha R, Saario, Susanna M, Niemi, Riku, Järvinen, Tomi, Laitinen, Jarmo T
Publicado em 2003

Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB(2) receptor

Por Savinainen, Juha R, Kokkola, Tarja, Salo, Outi M H, Poso, Antti, Järvinen, Tomi, Laitinen, Jarmo T
Publicado em 2005

Discovery of 12-Thiazole Abietanes as Selective Inhibitors of the Human Metabolic Serine Hydrolase hABHD16A

Por Ahonen, Tiina J., Savinainen, Juha R., Yli-Kauhaluoma, Jari, Kalso, Eija, Laitinen, Jarmo T., Moreira, Vânia M.
Publicado no ACS Med Chem Lett (2018)

Biochemical and Pharmacological Characterization of the Human Lymphocyte Antigen B-Associated Transcript 5 (BAT5/ABHD16A)

Por Savinainen, Juha R., Patel, Jayendra Z., Parkkari, Teija, Navia-Paldanius, Dina, Marjamaa, Joona J. T., Laitinen, Tuomo, Nevalainen, Tapio, Laitinen, Jarmo T.
Publicado em 2014

Discovery of Triterpenoids as Reversible Inhibitors of α/β-hydrolase Domain Containing 12 (ABHD12)

Por Parkkari, Teija, Haavikko, Raisa, Laitinen, Tuomo, Navia-Paldanius, Dina, Rytilahti, Roosa, Vaara, Miia, Lehtonen, Marko, Alakurtti, Sami, Yli-Kauhaluoma, Jari, Nevalainen, Tapio, Savinainen, Juha R., Laitinen, Jarmo T.
Publicado em 2014

Optimization of 1,2,5-Thiadiazole Carbamates as Potent and Selective ABHD6 Inhibitors ()

Por Patel, Jayendra Z., Nevalainen, Tapio J., Savinainen, Juha R., Adams, Yahaya, Laitinen, Tuomo, Runyon, Robert S., Vaara, Miia, Ahenkorah, Stephen, Kaczor, Agnieszka A., Navia-Paldanius, Dina, Gynther, Mikko, Aaltonen, Niina, Joharapurkar, Amit A., Jain, Mukul R., Haka, Abigail S., Maxfield, Frederick R., Laitinen, Jarmo T., Parkkari, Teija
Publicado no ChemMedChem (2014)