TLR4-dependent signaling drives extracellular catabolism of low-density lipoprotein aggregates

OBJECTIVE –: Aggregation and modification of low-density lipoproteins (LDL) promotes their retention and accumulation in the arteries. This is a critical initiating factor during atherosclerosis. Macrophage catabolism of aggregated LDL (agLDL) occurs using a specialized extracellular, hydrolytic com...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Singh, Rajesh K., Haka, Abigail S., Asmal, Arky, Barbosa-Lorenzi, Valéria C., Grosheva, Inna, Chin, Harvey F., Xiong, Yuquan, Hla, Timothy, Maxfield, Frederick R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928397/
https://ncbi.nlm.nih.gov/pubmed/31597445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.313200
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