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Macrophages Create an Acidic Extracellular Hydrolytic Compartment to Digest Aggregated Lipoproteins

A critical event in atherogenesis is the interaction of macrophages with subendothelial lipoproteins. Although most studies model this interaction by incubating macrophages with monomeric lipoproteins, macrophages in vivo encounter lipoproteins that are aggregated. The physical features of the lipop...

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Detalhes bibliográficos
Main Authors: Haka, Abigail S., Grosheva, Inna, Chiang, Ethan, Buxbaum, Adina R., Baird, Barbara A., Pierini, Lynda M., Maxfield, Frederick R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785736/
https://ncbi.nlm.nih.gov/pubmed/19812252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-07-0559
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