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Macrophages Create an Acidic Extracellular Hydrolytic Compartment to Digest Aggregated Lipoproteins

A critical event in atherogenesis is the interaction of macrophages with subendothelial lipoproteins. Although most studies model this interaction by incubating macrophages with monomeric lipoproteins, macrophages in vivo encounter lipoproteins that are aggregated. The physical features of the lipop...

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Hlavní autoři: Haka, Abigail S., Grosheva, Inna, Chiang, Ethan, Buxbaum, Adina R., Baird, Barbara A., Pierini, Lynda M., Maxfield, Frederick R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785736/
https://ncbi.nlm.nih.gov/pubmed/19812252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-07-0559
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