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Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse
Monocyte-derived cells use an extracellular, acidic, lytic compartment (a lysosomal synapse) for initial degradation of large objects or species bound to the extracellular matrix. Akin to osteoclast degradation of bone, extracellular catabolism is used by macrophages to degrade aggregates of low den...
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| Pubblicato in: | J Cell Sci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813320/ https://ncbi.nlm.nih.gov/pubmed/26801085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.181743 |
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