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Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse

Monocyte-derived cells use an extracellular, acidic, lytic compartment (a lysosomal synapse) for initial degradation of large objects or species bound to the extracellular matrix. Akin to osteoclast degradation of bone, extracellular catabolism is used by macrophages to degrade aggregates of low den...

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Dades bibliogràfiques
Publicat a:J Cell Sci
Autors principals: Singh, Rajesh K., Barbosa-Lorenzi, Valéria C., Lund, Frederik W., Grosheva, Inna, Maxfield, Frederick R., Haka, Abigail S.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813320/
https://ncbi.nlm.nih.gov/pubmed/26801085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.181743
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