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Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse

Monocyte-derived cells use an extracellular, acidic, lytic compartment (a lysosomal synapse) for initial degradation of large objects or species bound to the extracellular matrix. Akin to osteoclast degradation of bone, extracellular catabolism is used by macrophages to degrade aggregates of low den...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Sci
Prif Awduron: Singh, Rajesh K., Barbosa-Lorenzi, Valéria C., Lund, Frederik W., Grosheva, Inna, Maxfield, Frederick R., Haka, Abigail S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813320/
https://ncbi.nlm.nih.gov/pubmed/26801085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.181743
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