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High-density lipoprotein or cyclodextrin extraction of cholesterol from aggregated LDL reduces foam cell formation

Low-density lipoprotein (LDL) deposition, aggregation and retention in the endothelial sub-intima are critical initiating events during atherosclerosis. Macrophages digest aggregated LDL (agLDL) through a process called exophagy. High-density lipoprotein (HDL) plays an atheroprotective role, but stu...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Singh, Rajesh K., Lund, Frederik W., Haka, Abigail S., Maxfield, Frederick R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918773/
https://ncbi.nlm.nih.gov/pubmed/31719160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.237271
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