Targeting PI3K in Cancer: Any Good News?

Autor Martini, Miriam, Ciraolo, Elisa, Gulluni, Federico, Hirsch, Emilio
Vydáno 2013

Targeting PI3K/AKT/mTOR Signaling Pathway in Breast Cancer

Autor Li, Huayi, Prever, Lorenzo, Hirsch, Emilio, Gulluni, Federico
Vydáno v Cancers (Basel) (2021)

PI(3,4)P2 Signaling in Cancer and Metabolism

Autor Gozzelino, Luca, De Santis, Maria Chiara, Gulluni, Federico, Hirsch, Emilio, Martini, Miriam
Vydáno v Front Oncol (2020)

Downregulation of class II phosphoinositide 3-kinase PI3K-C2β delays cell division and potentiates the effect of docetaxel on cancer cell growth

Autor Cisse, Ouma, Quraishi, Muzthahid, Gulluni, Federico, Guffanti, Federica, Mavrommati, Ioanna, Suthanthirakumaran, Methushaa, Oh, Lara C. R., Schlatter, Jessica N., Sarvananthan, Ambisha, Broggini, Massimo, Hirsch, Emilio, Falasca, Marco, Maffucci, Tania
Vydáno v J Exp Clin Cancer Res (2019)

In vivo role of INPP4B in tumor and metastasis suppression through regulation of PI3K/AKT signaling at endosomes

Autor Chew, Chen Li, Lunardi, Andrea, Gulluni, Federico, Ruan, Daniel T., Chen, Ming, Salmena, Leonardo, Nishino, Michiya, Papa, Antonella, Ng, Christopher, Fung, Jacqueline, Clohessy, John G., Sasaki, Junko, Sasaki, Takehiko, Bronson, Roderick T., Hirsch, Emilio, Pandolfi, Pier Paolo
Vydáno v Cancer Discov (2015)

Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation

Autor Franco, Irene, Margaria, Jean Piero, De Santis, Maria Chiara, Ranghino, Andrea, Monteyne, Daniel, Chiaravalli, Marco, Pema, Monika, Campa, Carlo Cosimo, Ratto, Edoardo, Gulluni, Federico, Perez-Morga, David, Somlo, Stefan, Merlo, Giorgio R., Boletta, Alessandra, Hirsch, Emilio
Vydáno v J Am Soc Nephrol (2016)

PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function

Autor Franco, Irene, Gulluni, Federico, Campa, Carlo C., Costa, Carlotta, Margaria, Jean Piero, Ciraolo, Elisa, Martini, Miriam, Monteyne, Daniel, De Luca, Elisa, Germena, Giulia, Posor, York, Maffucci, Tania, Marengo, Stefano, Haucke, Volker, Falasca, Marco, Perez-Morga, David, Boletta, Alessandra, Merlo, Giorgio R., Hirsch, Emilio
Vydáno 2014

Mutations in PIK3C2A cause syndromic short stature, skeletal abnormalities, and cataracts associated with ciliary dysfunction

Autor Tiosano, Dov, Baris, Hagit N., Chen, Anlu, Hitzert, Marrit M., Schueler, Markus, Gulluni, Federico, Wiesener, Antje, Bergua, Antonio, Mory, Adi, Copeland, Brett, Gleeson, Joseph G., Rump, Patrick, van Meer, Hester, Sival, Deborah A., Haucke, Volker, Kriwinsky, Josh, Knaup, Karl X., Reis, André, Hauer, Nadine N., Hirsch, Emilio, Roepman, Ronald, Pfundt, Rolph, Thiel, Christian T., Wiesener, Michael S., Aslanyan, Mariam G., Buchner, David A.
Vydáno v PLoS Genet (2019)

PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation

Autor Gulluni, Federico, Prever, Lorenzo, Li, Huayi, Krafcikova, Petra, Corrado, Ilaria, Lo, Wen-Ting, Margaria, Jean Piero, Chen, Anlu, De Santis, Maria Chiara, Cnudde, Sophie J., Fogerty, Joseph, Yuan, Alex, Massarotti, Alberto, Sarijalo, Nasrin Torabi, Vadas, Oscar, Williams, Roger L., Thelen, Marcus, Powell, David R., Schüler, Markus, Wiesener, Michael S., Balla, Tamas, Baris, Hagit N., Tiosano, Dov, McDermott, Brian M., Perkins, Brian D., Ghigo, Alessandra, Martini, Miriam, Haucke, Volker, Boura, Evzen, Merlo, Giorgio Roberto, Buchner, David A., Hirsch, Emilio
Vydáno v Science (2021)