Generation of novel radiolabeled opiates through site-selective iodination

Por Majumdar, Susruta, Burgman, Maxim, Haselton, Nathan, Grinnell, Steven, Ocampo, Julia, Pasternak, Anna Rose, Pasternak, Gavril W
Publicado em 2011

Sandmeyer reaction repurposed for the site-selective, non-oxidizing radioiodination of fully-deprotected peptides: Studies on the endogenous opioid peptide α-neoendorphin

Por Pickett, Julie E., Nagakura, Kunihiko, Pasternak, Anna R., Grinnell, Steven G., Majumdar, Susruta, Lewis, Jason S., Pasternak, Gavril W.
Publicado em 2013

Pharmacologic Characterization in the Rat of a Potent Analgesic Lacking Respiratory Depression, IBNtxA

Por Grinnell, Steven G., Majumdar, Susruta, Narayan, Ankita, Le Rouzic, Valerie, Ansonoff, Michael, Pintar, John E., Pasternak, Gavril W.
Publicado em 2014

Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects

Por Majumdar, Susruta, Grinnell, Steven, Le Rouzic, Valerie, Burgman, Maxim, Polikar, Lisa, Ansonoff, Michael, Pintar, John, Pan, Ying-Xian, Pasternak, Gavril W.
Publicado em 2011

Novel 6β-acylaminomorphinans with analgesic activity

Por Váradi, András, Hosztafi, Sándor, Rouzic, Valerie Le, Tóth, Gergő, Urai, Ákos, Noszál, Béla, Pasternak, Gavril W., Grinnell, Steven G., Majumdar, Susruta
Publicado em 2013

Mild, Pd-catalyzed stannylation of radioiodination targets

Por Pickett, Julie E., Váradi, András, Palmer, Travis C., Grinnell, Steven G., Schrock, Joel M., Pasternak, Gavril W., Karimov, Rashad R., Majumdar, Susruta
Publicado no Bioorg Med Chem Lett (2015)

Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNS

Por Marrone, Gina F., Grinnell, Steven G., Lu, Zhigang, Rossi, Grace C., Le Rouzic, Valerie, Xu, Jin, Majumdar, Susruta, Pan, Ying-Xian, Pasternak, Gavril W.
Publicado no Proc Natl Acad Sci U S A (2016)

Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated mu opioid receptor (MOR-1) splice variants

Por Majumdar, Susruta, Subrath, Joan, Le Rouzic, Valerie, Polikar, Lisa, Burgman, Maxim, Nagakura, Kuni, Ocampo, Julie, Haselton, Nathan, Pasternak, Anna R., Grinnell, Steven, Pan, Ying-Xian, Pasternak, Gavril W.
Publicado em 2012

Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants

Por Grinnell, Steven G., Ansonoff, Michael, Marrone, Gina F., Lu, Zhigang, Narayan, Ankita, Xu, Jin, Rossi, Grace, Majumdar, Susruta, Pan, Ying-Xian, Bassoni, Daniel L., Pintar, John, Pasternak, Gavril
Publicado no Synapse (2016)

Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2

Por Váradi, András, Marrone, Gina F., Palmer, Travis C., Narayan, Ankita, Szabó, Márton R., Le Rouzic, Valerie, Grinnell, Steven G., Subrath, Joan J., Warner, Evelyn, Kalra, Sanjay, Hunkele, Amanda, Pagirsky, Jeremy, Eans, Shainnel O., Medina, Jessica M., Xu, Jin, Pan, Ying-Xian, Borics, Attila, Pasternak, Gavril W., McLaughlin, Jay P., Majumdar, Susruta
Publicado no J Med Chem (2016)