The magnitude of hedgehog signaling activity defines skin tumor phenotype

Por Grachtchouk, Vladimir, Grachtchouk, Marina, Lowe, Lori, Johnson, Tim, Wei, Lebing, Wang, Aiqin, de Sauvage, Fred, Dlugosz, Andrzej A.
Publicado em 2003

Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development

Por Mill, Pleasantine, Mo, Rong, Fu, Hong, Grachtchouk, Marina, Kim, Peter C.W., Dlugosz, Andrzej A., Hui, Chi-chung
Publicado em 2003

Odontogenic Keratocysts Arise from Quiescent Epithelial Rests and Are Associated with Deregulated Hedgehog Signaling in Mice and Humans

Por Grachtchouk, Marina, Liu, Jianhong, Wang, Aiqin, Wei, Lebing, Bichakjian, Christopher K., Garlick, Jonathan, Paulino, Augusto F., Giordano, Thomas, Dlugosz, Andrzej A.
Publicado em 2006

Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling

Por Ermilov, Alexandre N., Kumari, Archana, Li, Libo, Joiner, Ariell M., Grachtchouk, Marina A., Allen, Benjamin L., Dlugosz, Andrzej A., Mistretta, Charlotte M.
Publicado no PLoS Genet (2016)

Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle

Por Hutchin, Mark E., Kariapper, Muhammed S.T., Grachtchouk, Marina, Wang, Aiqin, Wei, Lebing, Cummings, Donelle, Liu, Jianhong, Michael, L. Evan, Glick, Adam, Dlugosz, Andrzej A.
Publicado em 2005

Hedgehog Signaling Regulates Sebaceous Gland Development

Por Allen, Mary, Grachtchouk, Marina, Sheng, Hong, Grachtchouk, Vladimir, Wang, Anna, Wei, Lebing, Liu, Jianhong, Ramirez, Angel, Metzger, Daniel, Chambon, Pierre, Jorcano, Jose, Dlugosz, Andrzej A.
Publicado em 2003

Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways

Por Sharov, Andrey A., Mardaryev, Andrei N., Sharova, Tatyana Y., Grachtchouk, Marina, Atoyan, Ruzanna, Byers, H. Randolph, Seykora, John T., Overbeek, Paul, Dlugosz, Andrzej, Botchkarev, Vladimir A.
Publicado em 2009

Transgenic expression of human amphiregulin in mouse skin: inflammatory epidermal hyperplasia and enlarged sebaceous glands

Por Li, Yong, Stoll, Stefan W., Sekhon, Sahil, Talsma, Caroline, Camhi, Maya I., Jones, Jennifer L., Lambert, Sylviane, Marley, Hue, Rittié, Laure, Grachtchouk, Marina, Fritz, Yi, Ward, Nicole L., Elder, James T.
Publicado no Exp Dermatol (2016)

Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes

Por Dentice, Monica, Luongo, Cristina, Huang, Stephen, Ambrosio, Raffaele, Elefante, Antonia, Mirebeau-Prunier, Delphine, Zavacki, Ann Marie, Fenzi, Gianfranco, Grachtchouk, Marina, Hutchin, Mark, Dlugosz, Andrzej A., Bianco, Antonio C., Missero, Caterina, Larsen, P. Reed, Salvatore, Domenico
Publicado em 2007

Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations

Por Grachtchouk, Marina, Pero, Joanna, Yang, Steven H., Ermilov, Alexandre N., Michael, L. Evan, Wang, Aiqin, Wilbert, Dawn, Patel, Rajiv M., Ferris, Jennifer, Diener, James, Allen, Mary, Lim, Seokchun, Syu, Li-Jyun, Verhaegen, Monique, Dlugosz, Andrzej A.
Publicado em 2011

Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways

Por Syu, Li-Jyun, Zhao, Xinyi, Zhang, Yaqing, Grachtchouk, Marina, Demitrack, Elise, Ermilov, Alexandre, Wilbert, Dawn M., Zheng, Xinlei, Kaatz, Ashley, Greenson, Joel K., Gumucio, Deborah L., Merchant, Juanita L., di Magliano, Marina Pasca, Samuelson, Linda C., Dlugosz, Andrzej A.
Publicado no Oncotarget (2016)

Transgenic Expression of Interferon-γ in Mouse Stomach Leads to Inflammation, Metaplasia, and Dysplasia

Por Syu, Li-Jyun, El-Zaatari, Mohamad, Eaton, Kathryn A., Liu, Zhiping, Tetarbe, Manas, Keeley, Theresa M., Pero, Joanna, Ferris, Jennifer, Wilbert, Dawn, Kaatz, Ashley, Zheng, Xinlei, Qiao, Xiotan, Grachtchouk, Marina, Gumucio, Deborah L., Merchant, Juanita L., Samuelson, Linda C., Dlugosz, Andrzej A.
Publicado em 2012