Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations

Uncontrolled Hedgehog (Hh) signaling leads to the development of basal cell carcinoma (BCC), the most common human cancer, but the cell of origin for BCC is unclear. While Hh pathway dysregulation is common to essentially all BCCs, there exist multiple histological subtypes, including superficial an...

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Autori principali: Grachtchouk, Marina, Pero, Joanna, Yang, Steven H., Ermilov, Alexandre N., Michael, L. Evan, Wang, Aiqin, Wilbert, Dawn, Patel, Rajiv M., Ferris, Jennifer, Diener, James, Allen, Mary, Lim, Seokchun, Syu, Li-Jyun, Verhaegen, Monique, Dlugosz, Andrzej A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083781/
https://ncbi.nlm.nih.gov/pubmed/21519145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46307
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