Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations

Uncontrolled Hedgehog (Hh) signaling leads to the development of basal cell carcinoma (BCC), the most common human cancer, but the cell of origin for BCC is unclear. While Hh pathway dysregulation is common to essentially all BCCs, there exist multiple histological subtypes, including superficial an...

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Detalhes bibliográficos
Main Authors: Grachtchouk, Marina, Pero, Joanna, Yang, Steven H., Ermilov, Alexandre N., Michael, L. Evan, Wang, Aiqin, Wilbert, Dawn, Patel, Rajiv M., Ferris, Jennifer, Diener, James, Allen, Mary, Lim, Seokchun, Syu, Li-Jyun, Verhaegen, Monique, Dlugosz, Andrzej A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083781/
https://ncbi.nlm.nih.gov/pubmed/21519145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46307
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