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Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations
Uncontrolled Hedgehog (Hh) signaling leads to the development of basal cell carcinoma (BCC), the most common human cancer, but the cell of origin for BCC is unclear. While Hh pathway dysregulation is common to essentially all BCCs, there exist multiple histological subtypes, including superficial an...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083781/ https://ncbi.nlm.nih.gov/pubmed/21519145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46307 |
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