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Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development

Sonic hedgehog (Shh) signaling plays a critical role in hair follicle development and skin cancer, but how it controls these processes remains unclear. Of the three Gli transcription factors involved in transducing Shh signals in vertebrates, we demonstrate here that Gli2 is the key mediator of Shh...

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Detalhes bibliográficos
Main Authors: Mill, Pleasantine, Mo, Rong, Fu, Hong, Grachtchouk, Marina, Kim, Peter C.W., Dlugosz, Andrzej A., Hui, Chi-chung
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC195973/
https://ncbi.nlm.nih.gov/pubmed/12533516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1038103
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