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Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development

Sonic hedgehog (Shh) signaling plays a critical role in hair follicle development and skin cancer, but how it controls these processes remains unclear. Of the three Gli transcription factors involved in transducing Shh signals in vertebrates, we demonstrate here that Gli2 is the key mediator of Shh...

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Autors principals: Mill, Pleasantine, Mo, Rong, Fu, Hong, Grachtchouk, Marina, Kim, Peter C.W., Dlugosz, Andrzej A., Hui, Chi-chung
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC195973/
https://ncbi.nlm.nih.gov/pubmed/12533516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1038103
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