Učitavanje...

Odontogenic Keratocysts Arise from Quiescent Epithelial Rests and Are Associated with Deregulated Hedgehog Signaling in Mice and Humans

Odontogenic keratocysts in humans are aggressive, noninflammatory jaw cysts that may harbor PTCH1 mutations, leading to constitutive activity of the embryonic Hedgehog (Hh) signaling pathway. We show here that epithelial expression of the Hh transcriptional effector Gli2 is sufficient for highly pen...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Grachtchouk, Marina, Liu, Jianhong, Wang, Aiqin, Wei, Lebing, Bichakjian, Christopher K., Garlick, Jonathan, Paulino, Augusto F., Giordano, Thomas, Dlugosz, Andrzej A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698812/
https://ncbi.nlm.nih.gov/pubmed/16936257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060054
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!