Transgenic Expression of Interferon-γ in Mouse Stomach Leads to Inflammation, Metaplasia, and Dysplasia

Gastric adenocarcinoma is one of the leading causes of cancer mortality worldwide. It arises through a stepwise process that includes prominent inflammation with expression of interferon-γ (IFN-γ) and multiple other pro-inflammatory cytokines. We engineered mice expressing IFN-γ under the control of...

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Главные авторы: Syu, Li-Jyun, El-Zaatari, Mohamad, Eaton, Kathryn A., Liu, Zhiping, Tetarbe, Manas, Keeley, Theresa M., Pero, Joanna, Ferris, Jennifer, Wilbert, Dawn, Kaatz, Ashley, Zheng, Xinlei, Qiao, Xiotan, Grachtchouk, Marina, Gumucio, Deborah L., Merchant, Juanita L., Samuelson, Linda C., Dlugosz, Andrzej A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2012
Предметы:
Regular Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509761/
https://ncbi.nlm.nih.gov/pubmed/23036899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.08.017
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