Type 3 Deiodinase and Consumptive Hypothyroidism: A Common Mechanism for a Rare Disease

Por Luongo, Cristina, Trivisano, Luigi, Alfano, Fausta, Salvatore, Domenico
Publicado em 2013

The Sonic Hedgehog-Induced Type 3 Deiodinase Facilitates Tumorigenesis of Basal Cell Carcinoma by Reducing Gli2 Inactivation

Por Luongo, Cristina, Ambrosio, Raffaele, Salzano, Salvatore, Dlugosz, Andrzej A., Missero, Caterina, Dentice, Monica
Publicado no Endocrinology (2014)

Transcription Factor Nkx-2.5 Induces Sodium/Iodide Symporter Gene Expression and Participates in Retinoic Acid- and Lactation-Induced Transcription in Mammary Cells

Por Dentice, Monica, Luongo, Cristina, Elefante, Antonia, Romino, Romina, Ambrosio, Raffaele, Vitale, Mario, Rossi, Guido, Fenzi, Gianfranco, Salvatore, Domenico
Publicado em 2004

Pendrin Is a Novel In Vivo Downstream Target Gene of the TTF-1/Nkx-2.1 Homeodomain Transcription Factor in Differentiated Thyroid Cells

Por Dentice, Monica, Luongo, Cristina, Elefante, Antonia, Ambrosio, Raffaele, Salzano, Salvatore, Zannini, Mariastella, Nitsch, Roberto, Di Lauro, Roberto, Rossi, Guido, Fenzi, Gianfranco, Salvatore, Domenico
Publicado em 2005

The Selective Loss of the Type 2 Iodothyronine Deiodinase in Mouse Thyrotrophs Increases Basal TSH but Blunts the Thyrotropin Response to Hypothyroidism

Por Luongo, Cristina, Martin, Cecilia, Vella, Kristen, Marsili, Alessandro, Ambrosio, Raffaele, Dentice, Monica, Harney, John W., Salvatore, Domenico, Zavacki, Ann Marie, Larsen, P. Reed
Publicado no Endocrinology (2015)

Catalysis leads to post-translational inactivation of the Type 1 deiodinase and alters its conformation

Por Zhu, Bo, Shrivastava, Ashutosh, Luongo, Cristina, Chen, Ting, Harney, John W., Marsili, Alessandro, Tran, Thuy-Van, Bhadouria, Anulika, Mopala, Radhika, Steen, Amanda I., Larsen, P. Reed, Zavacki, Ann Marie
Publicado em 2012

The Thyroid Hormone-Inactivating Deiodinase Functions as a Homodimer

Por Sagar, G. D. Vivek, Gereben, Balázs, Callebaut, Isabelle, Mornon, Jean-Paul, Zeöld, Anikó, Curcio-Morelli, Cyntia, Harney, John W., Luongo, Cristina, Mulcahey, Michelle A., Larsen, P. Reed, Huang, Stephen A., Bianco, Antonio C.
Publicado em 2008

Intracellular Inactivation of Thyroid Hormone Is a Survival Mechanism for Muscle Stem Cell Proliferation and Lineage Progression

Por Dentice, Monica, Ambrosio, Raffaele, Damiano, Valentina, Sibilio, Annarita, Luongo, Cristina, Guardiola, Ombretta, Yennek, Siham, Zordan, Paola, Minchiotti, Gabriella, Colao, Annamaria, Marsili, Alessandro, Brunelli, Silvia, Del Vecchio, Luigi, Larsen, P. Reed, Tajbakhsh, Shahragim, Salvatore, Domenico
Publicado no Cell Metab (2014)

Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway–driven skin tumorigenesis

Por Di Girolamo, Daniela, Ambrosio, Raffaele, De Stefano, Maria A., Mancino, Giuseppina, Porcelli, Tommaso, Luongo, Cristina, Di Cicco, Emery, Scalia, Giulia, Vecchio, Luigi Del, Colao, Annamaria, Dlugosz, Andrzej A., Missero, Caterina, Salvatore, Domenico, Dentice, Monica
Publicado no J Clin Invest (2016)

Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes

Por Dentice, Monica, Luongo, Cristina, Huang, Stephen, Ambrosio, Raffaele, Elefante, Antonia, Mirebeau-Prunier, Delphine, Zavacki, Ann Marie, Fenzi, Gianfranco, Grachtchouk, Marina, Hutchin, Mark, Dlugosz, Andrzej A., Bianco, Antonio C., Missero, Caterina, Larsen, P. Reed, Salvatore, Domenico
Publicado em 2007

Ubiquitination-Induced Conformational Change within the Deiodinase Dimer Is a Switch Regulating Enzyme Activity

Por Sagar, G. D. Vivek, Gereben, Balázs, Callebaut, Isabelle, Mornon, Jean-Paul, Zeöld, Anikó, da Silva, Wagner S., Luongo, Cristina, Dentice, Monica, Tente, Susana M., Freitas, Beatriz C. G., Harney, John W., Zavacki, Ann Marie, Bianco, Antonio C.
Publicado em 2007

Mice With Hepatocyte-Specific Deficiency of Type 3 Deiodinase Have Intact Liver Regeneration and Accelerated Recovery From Nonthyroidal Illness After Toxin-Induced Hepatonecrosis

Por Castroneves, Luciana A., Jugo, Rebecca H., Maynard, Michelle A., Lee, Jennifer S., Wassner, Ari J., Dorfman, David, Bronson, Roderick T., Ukomadu, Chinweike, Agoston, Agoston T., Ding, Lai, Luongo, Cristina, Guo, Cuicui, Song, Huaidong, Demchev, Valeriy, Lee, Nicholas Y., Feldman, Henry A., Vella, Kristen R., Peake, Roy W., Hartigan, Christina, Kellogg, Mark D., Desai, Anal, Salvatore, Domenico, Dentice, Monica, Huang, Stephen A.
Publicado em 2014