Transcription Factor Nkx-2.5 Induces Sodium/Iodide Symporter Gene Expression and Participates in Retinoic Acid- and Lactation-Induced Transcription in Mammary Cells

The sodium/iodide symporter (NIS) is a plasma membrane protein that mediates active iodide transport in thyroid and mammary cells. It is a prerequisite for radioiodide treatment of thyroid cancer and a promising diagnostic and therapeutic tool for breast cancer. We investigated the molecular mechani...

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Detalhes bibliográficos
Main Authors: Dentice, Monica, Luongo, Cristina, Elefante, Antonia, Romino, Romina, Ambrosio, Raffaele, Vitale, Mario, Rossi, Guido, Fenzi, Gianfranco, Salvatore, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC515029/
https://ncbi.nlm.nih.gov/pubmed/15340050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.7863-7877.2004
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