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The Sonic Hedgehog-Induced Type 3 Deiodinase Facilitates Tumorigenesis of Basal Cell Carcinoma by Reducing Gli2 Inactivation
Thyroid hormone (TH) is an important regulator of growth, development, and metabolism. Most of the active TH T(3) is generated by peripheral TH metabolism mediated by the iodothyronine deiodinases. Type 3 deiodinase (D3) inactivates T(3) via specific deiodination reactions. It is an oncofetal protei...
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| Publicado no: | Endocrinology |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5393316/ https://ncbi.nlm.nih.gov/pubmed/24693967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2108 |
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