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The Sonic Hedgehog-Induced Type 3 Deiodinase Facilitates Tumorigenesis of Basal Cell Carcinoma by Reducing Gli2 Inactivation
Thyroid hormone (TH) is an important regulator of growth, development, and metabolism. Most of the active TH T(3) is generated by peripheral TH metabolism mediated by the iodothyronine deiodinases. Type 3 deiodinase (D3) inactivates T(3) via specific deiodination reactions. It is an oncofetal protei...
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| Pubblicato in: | Endocrinology |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Endocrine Society
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5393316/ https://ncbi.nlm.nih.gov/pubmed/24693967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2108 |
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