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The Sonic Hedgehog-Induced Type 3 Deiodinase Facilitates Tumorigenesis of Basal Cell Carcinoma by Reducing Gli2 Inactivation

Thyroid hormone (TH) is an important regulator of growth, development, and metabolism. Most of the active TH T(3) is generated by peripheral TH metabolism mediated by the iodothyronine deiodinases. Type 3 deiodinase (D3) inactivates T(3) via specific deiodination reactions. It is an oncofetal protei...

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書目詳細資料
發表在:Endocrinology
Main Authors: Luongo, Cristina, Ambrosio, Raffaele, Salzano, Salvatore, Dlugosz, Andrzej A., Missero, Caterina, Dentice, Monica
格式: Artigo
語言:Inglês
出版: Endocrine Society 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393316/
https://ncbi.nlm.nih.gov/pubmed/24693967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2108
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