Efficient Incorporation of Multiple Selenocysteines Involves an Inefficient Decoding Step Serving as a Potential Translational Checkpoint and Ribosome Bottleneck

Por Stoytcheva, Zoia, Tujebajeva, Rosa M., Harney, John W., Berry, Marla J.
Publicado em 2006

Physiological role and regulation of iodothyronine deiodinases: a 2011 update

Por Marsili, Alessandro, Zavacki, Ann Marie, Harney, John W., Larsen, P. Reed
Publicado em 2011

SECIS–SBP2 interactions dictate selenocysteine incorporation efficiency and selenoprotein hierarchy

Por Low, Susan C., Grundner-Culemann, Elisabeth, Harney, John W., Berry, Marla J.
Publicado em 2000

Type 2 iodothyronine deiodinase is the major source of plasma T(3) in euthyroid humans

Por Maia, Ana Luiza, Kim, Brian W., Huang, Stephen A., Harney, John W., Larsen, P. Reed
Publicado em 2005

Inflammation-Inducible Type 2 Deiodinase Expression in the Leptomeninges, Choroid Plexus, and at Brain Blood Vessels in Male Rodents

Por Wittmann, Gábor, Harney, John W., Singru, Praful S., Nouriel, Shira S., Reed Larsen, P., Lechan, Ronald M.
Publicado em 2014

Substitution of Serine for Proline in the Active Center of Type 2 Iodothyronine Deiodinase Substantially Alters Its in Vitro Biochemical Properties with Dithiothreitol But Not Its...

Por Goemann, Iuri Martin, Gereben, Balázs, Harney, John W., Zhu, Bo, Maia, Ana Luiza, Larsen, P. Reed
Publicado em 2010

Thyroxine-induced induction of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase

Por Marsili, Alessandro, Sanchez, Edith, Singru, Praful, Harney, John W., Zavacki, Ann Marie, Lechan, Ronald M., Larsen, P. Reed
Publicado em 2011

Type II iodothyronine deiodinase provides intracellular 3,5,3′-triiodothyronine to normal and regenerating mouse skeletal muscle

Por Marsili, Alessandro, Tang, Dan, Harney, John W., Singh, Prabhat, Zavacki, Ann Marie, Dentice, Monica, Salvatore, Domenico, Larsen, P. Reed
Publicado em 2011

Activation of Thyroid Hormone Is Transcriptionally Regulated by Epidermal Growth Factor in Human Placenta-Derived JEG3 Cells

Por Canettieri, Gianluca, Franchi, Antonella, Della Guardia, Michele, Morantte, Ianessa, Santaguida, Maria Giulia, Harney, John W., Larsen, P. Reed, Centanni, Marco
Publicado em 2008

The Selective Loss of the Type 2 Iodothyronine Deiodinase in Mouse Thyrotrophs Increases Basal TSH but Blunts the Thyrotropin Response to Hypothyroidism

Por Luongo, Cristina, Martin, Cecilia, Vella, Kristen, Marsili, Alessandro, Ambrosio, Raffaele, Dentice, Monica, Harney, John W., Salvatore, Domenico, Zavacki, Ann Marie, Larsen, P. Reed
Publicado no Endocrinology (2015)

The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue

Por de Jesus, Lucia A., Carvalho, Suzy D., Ribeiro, Mirian O., Schneider, Mark, Kim, Sung-Woo, Harney, John W., Larsen, P. Reed, Bianco, Antonio C.
Publicado em 2001

Decoding apparatus for eukaryotic selenocysteine insertion

Por Tujebajeva, Rosa M., Copeland, Paul R., Xu, Xue-Ming, Carlson, Bradley A., Harney, John W., Driscoll, Donna M., Hatfield, Dolph L., Berry, Marla J.
Publicado em 2000

Deubiquitination of type 2 iodothyronine deiodinase by von Hippel–Lindau protein–interacting deubiquitinating enzymes regulates thyroid hormone activation

Por Curcio-Morelli, Cyntia, Zavacki, Ann Marie, Christofollete, Marcelo, Gereben, Balazs, de Freitas, Beatriz C.G., Harney, John W., Li, Zaibo, Wu, Guan, Bianco, Antonio C.
Publicado em 2003

Nuclear Assembly of UGA Decoding Complexes on Selenoprotein mRNAs: a Mechanism for Eluding Nonsense-Mediated Decay?

Por de Jesus, Lucia A., Hoffmann, Peter R., Michaud, Tanya, Forry, Erin P., Small-Howard, Andrea, Stillwell, Robert J., Morozova, Nadya, Harney, John W., Berry, Marla J.
Publicado em 2006

The E3 Ubiquitin Ligase TEB4 Mediates Degradation of Type 2 Iodothyronine Deiodinase

Por Zavacki, Ann Marie, Arrojo e Drigo, Rafael, Freitas, Beatriz C. G., Chung, Mirra, Harney, John W., Egri, Péter, Wittmann, Gábor, Fekete, Csaba, Gereben, Balázs, Bianco, Antonio C.
Publicado em 2009

Thyroid Hormone Activation in Vascular Smooth Muscle Cells Is Negatively Regulated by Glucocorticoid

Por Toyoda, Nagaoki, Yasuzawa-Amano, Saori, Nomura, Emiko, Yamauchi, Azusa, Nishimura, Kumiko, Ukita, Chizuko, Morimoto, Satoshi, Kosaki, Atsushi, Iwasaka, Toshiji, Harney, John W., Larsen, P. Reed, Nishikawa, Mitsushige
Publicado em 2009

Supramolecular Complexes Mediate Selenocysteine Incorporation In Vivo

Por Small-Howard, Andrea, Morozova, Nadya, Stoytcheva, Zoia, Forry, Erin P., Mansell, John B., Harney, John W., Carlson, Bradley A., Xu, Xue-ming, Hatfield, Dolph L., Berry, Marla J.
Publicado em 2006

Catalysis leads to post-translational inactivation of the Type 1 deiodinase and alters its conformation

Por Zhu, Bo, Shrivastava, Ashutosh, Luongo, Cristina, Chen, Ting, Harney, John W., Marsili, Alessandro, Tran, Thuy-Van, Bhadouria, Anulika, Mopala, Radhika, Steen, Amanda I., Larsen, P. Reed, Zavacki, Ann Marie
Publicado em 2012

The Thyroid Hormone-Inactivating Deiodinase Functions as a Homodimer

Por Sagar, G. D. Vivek, Gereben, Balázs, Callebaut, Isabelle, Mornon, Jean-Paul, Zeöld, Anikó, Curcio-Morelli, Cyntia, Harney, John W., Luongo, Cristina, Mulcahey, Michelle A., Larsen, P. Reed, Huang, Stephen A., Bianco, Antonio C.
Publicado em 2008

Ubiquitination-Induced Conformational Change within the Deiodinase Dimer Is a Switch Regulating Enzyme Activity

Por Sagar, G. D. Vivek, Gereben, Balázs, Callebaut, Isabelle, Mornon, Jean-Paul, Zeöld, Anikó, da Silva, Wagner S., Luongo, Cristina, Dentice, Monica, Tente, Susana M., Freitas, Beatriz C. G., Harney, John W., Zavacki, Ann Marie, Bianco, Antonio C.
Publicado em 2007