Type II iodothyronine deiodinase provides intracellular 3,5,3′-triiodothyronine to normal and regenerating mouse skeletal muscle

The FoxO3-dependent increase in type II deiodinase (D2), which converts the prohormone thyroxine (T(4)) to 3,5,3′-triiodothyronine (T(3)), is required for normal mouse skeletal muscle differentiation and regeneration. This implies a requirement for an increase in D2-generated intracellular T(3) unde...

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Hlavní autoři: Marsili, Alessandro, Tang, Dan, Harney, John W., Singh, Prabhat, Zavacki, Ann Marie, Dentice, Monica, Salvatore, Domenico, Larsen, P. Reed
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214000/
https://ncbi.nlm.nih.gov/pubmed/21771965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00292.2011
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