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Type 2 Iodothyronine Deiodinase Levels Are Higher in Slow-Twitch than Fast-Twitch Mouse Skeletal Muscle and Are Increased in Hypothyroidism

Because of its large mass, relatively high metabolic activity and responsiveness to thyroid hormone, skeletal muscle contributes significantly to energy expenditure. Despite the presence of mRNA encoding the type 2 iodothyronine-deiodinase (D2), an enzyme that activates T(4) to T3, very low or undet...

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Main Authors: Marsili, Alessandro, Ramadan, Waile, Harney, John W., Mulcahey, Michelle, Castroneves, Luciana Audi, Goemann, Iuri Martin, Wajner, Simone Magagnin, Huang, Stephen A., Zavacki, Ann Marie, Maia, Ana Luiza, Dentice, Monica, Salvatore, Domenico, Silva, J. Enrique, Larsen, P. Reed
Format: Artigo
Jezik:Inglês
Izdano: The Endocrine Society 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999482/
https://ncbi.nlm.nih.gov/pubmed/20881246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0631
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