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Scope and limitations of iodothyronine deiodinases in hypothyroidism

The coordinated expression and activity of the iodothyronine deiodinases regulate thyroid hormone levels in hypothyroidism. Once heralded as the pathway underpinning adequate thyroid-hormone replacement therapy with levothyroxine, the role of these enzymes has come into question as they have been im...

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Detalhes bibliográficos
Publicado no:Nat Rev Endocrinol
Main Authors: Gereben, Balázs, McAninch, Elizabeth A., Ribeiro, Miriam O., Bianco, Antonio C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003781/
https://ncbi.nlm.nih.gov/pubmed/26416219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrendo.2015.155
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