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Scope and limitations of iodothyronine deiodinases in hypothyroidism

The coordinated expression and activity of the iodothyronine deiodinases regulate thyroid hormone levels in hypothyroidism. Once heralded as the pathway underpinning adequate thyroid-hormone replacement therapy with levothyroxine, the role of these enzymes has come into question as they have been im...

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Podrobná bibliografie
Vydáno v:Nat Rev Endocrinol
Hlavní autoři: Gereben, Balázs, McAninch, Elizabeth A., Ribeiro, Miriam O., Bianco, Antonio C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003781/
https://ncbi.nlm.nih.gov/pubmed/26416219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrendo.2015.155
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