Thyroxine-induced induction of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase

Suppression of TSH release from the hypothyroid thyrotrophs is one of the most rapid effects of T3 or T4. It is initiated within an hour, and precedes the decrease in TSHβ mRNA inhibition and is blocked by inhibitors of mRNA or protein synthesis. TSH elevation in primary hypothyroidism requires both...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Marsili, Alessandro, Sanchez, Edith, Singru, Praful, Harney, John W., Zavacki, Ann Marie, Lechan, Ronald M., Larsen, P. Reed
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558748/
https://ncbi.nlm.nih.gov/pubmed/21788297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-11-0248
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados