Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways

Bone morphogenetic proteins (BMPs) play pivotal roles in the regulation of skin development. To study the role of BMPs in skin tumorigenesis, BMP antagonist noggin was used to generate keratin 14-targeted transgenic mice. In contrast to wild-type mice, transgenic mice developed spontaneous hair foll...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sharov, Andrey A., Mardaryev, Andrei N., Sharova, Tatyana Y., Grachtchouk, Marina, Atoyan, Ruzanna, Byers, H. Randolph, Seykora, John T., Overbeek, Paul, Dlugosz, Andrzej, Botchkarev, Vladimir A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731148/
https://ncbi.nlm.nih.gov/pubmed/19700758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090163
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados