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Bone morphogenetic protein signalling suppresses wound-induced skin repair by inhibiting keratinocyte proliferation and migration

Bone morphogenetic protein (BMP) signalling plays a key role in the control of skin development and postnatal remodelling by regulating keratinocyte proliferation, differentiation and apoptosis. To study the role of BMPs in wound-induced epidermal repair, we used transgenic mice overexpressing the B...

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Detalhes bibliográficos
Main Authors: Lewis, Christopher J., Mardaryev, Andrei N., Poterlowicz, Krzysztof, Sharova, Tatyana Y., Aziz, Ahmar, Sharpe, David T., Botchkareva, Natalia V., Sharov, Andrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945401/
https://ncbi.nlm.nih.gov/pubmed/24126843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.419
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