Human Germ Cell Tumors are Developmental Cancers: Impact of Epigenetics on Pathobiology and Clinic

Yazar: Lobo, João, Gillis, Ad J. M., Jerónimo, Carmen, Henrique, Rui, Looijenga, Leendert H. J.
Yayımlandı Int J Mol Sci (2019)

Prediction of relapse in stage I testicular germ cell tumor patients on surveillance: investigation of biomarkers

Yazar: Lobo, João, Gillis, Ad J. M., van den Berg, Annette, Looijenga, Leendert H. J.
Yayımlandı BMC Cancer (2020)

VASA mRNA (DDX4) detection is more specific than immunohistochemistry using poly- or monoclonal antibodies for germ cells in the male urogenital tract

Yazar: Boellaard, Willem P.A., Stoop, Hans, Gillis, Ad J.M., Oosterhuis, J. Wolter., Looijenga, Leendert H.J.
Yayımlandı Medicine (Baltimore) (2017)

Role of SOX2 in the Etiology of Embryonal Carcinoma, Based on Analysis of the NCCIT and NT2 Cell Lines

Yazar: Eini, Ronak, Stoop, Hans, Gillis, Ad J. M., Biermann, Katharina, Dorssers, Lambert C. J., Looijenga, Leendert H. J.
Baskı/Yayın Bilgisi 2014

Cripto: Expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors

Yazar: Spiller, Cassy M., Gillis, Ad J.M., Burnet, Guillaume, Stoop, Hans, Koopman, Peter, Bowles, Josephine, Looijenga, Leendert H.J.
Yayımlandı Mol Oncol (2015)

CRIPTO and miR-371a-3p Are Serum Biomarkers of Testicular Germ Cell Tumors and Are Detected in Seminal Plasma from Azoospermic Males

Yazar: Spiller, Cassy M., Lobo, João, Boellaard, Willem P. A., Gillis, Ad J. M., Bowles, Josephine, Looijenga, Leendert H. J.
Yayımlandı Cancers (Basel) (2020)

Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors

Yazar: Rijlaarsdam, Martin A., Tax, David M. J., Gillis, Ad J. M., Dorssers, Lambert C. J., Koestler, Devin C., de Ridder, Jeroen, Looijenga, Leendert H. J.
Yayımlandı PLoS One (2015)

A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours

Yazar: Murray, Matthew J, Bell, Emma, Raby, Katie L, Rijlaarsdam, Martin A, Gillis, Ad J M, Looijenga, Leendert H J, Brown, Helen, Destenaves, Benoit, Nicholson, James C, Coleman, Nicholas
Yayımlandı Br J Cancer (2016)

XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality

Yazar: Lobo, João, Nunes, Sandra P., Gillis, Ad J. M., Barros-Silva, Daniela, Miranda-Gonçalves, Vera, van den Berg, Annette, Cantante, Mariana, Guimarães, Rita, Henrique, Rui, Jerónimo, Carmen, Looijenga, Leendert H. J.
Yayımlandı Cancers (Basel) (2019)

Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline

Yazar: Giannoulatou, Eleni, Maher, Geoffrey J., Ding, Zhihao, Gillis, Ad J. M., Dorssers, Lambert C. J., Hoischen, Alexander, Rajpert-De Meyts, Ewa, McVean, Gilean, Wilkie, Andrew O. M., Looijenga, Leendert H. J., Goriely, Anne
Yayımlandı PLoS One (2017)

The MicroRNA-371 Family as Plasma Biomarkers for Monitoring Undifferentiated and Potentially Malignant Human Pluripotent Stem Cells in Teratoma Assays

Yazar: Salvatori, Daniela C.F., Dorssers, Lambert C.J., Gillis, Ad J.M., Perretta, Gemma, van Agthoven, Ton, Gomes Fernandes, Maria, Stoop, Hans, Prins, Jan-Bas, Oosterhuis, J. Wolter, Mummery, Christine, Looijenga, Leendert H.J.
Yayımlandı Stem Cell Reports (2018)

Seminoma and Embryonal Carcinoma Footprints Identified by Analysis of Integrated Genome-Wide Epigenetic and Expression Profiles of Germ Cell Cancer Cell Lines

Yazar: van der Zwan, Yvonne G., Rijlaarsdam, Martin A., Rossello, Fernando J., Notini, Amanda J., de Boer, Suzan, Watkins, D. Neil, Gillis, Ad J. M., Dorssers, Lambert C. J., White, Stefan J., Looijenga, Leendert H. J.
Baskı/Yayın Bilgisi 2014

Molecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development

Yazar: Dorssers, Lambert C. J., Gillis, Ad J. M., Stoop, Hans, van Marion, Ronald, Nieboer, Marleen M., van Riet, Job, van de Werken, Harmen J. G., Oosterhuis, J. Wolter, de Ridder, Jeroen, Looijenga, Leendert H. J.
Yayımlandı Br J Cancer (2019)

Restricted 12p Amplification and RAS Mutation in Human Germ Cell Tumors of the Adult Testis

Yazar: Roelofs, Helene, Mostert, Marijke C., Pompe, Kirsten, Zafarana, Gaetano, van Oorschot, Monique, van Gurp, Ruud J. H. L. M., Gillis, Ad J. M., Stoop, Hans, Beverloo, Berna, Oosterhuis, J. Wolter, Bokemeyer, Carsten, Looijenga, Leendert H. J.
Baskı/Yayın Bilgisi 2000

Napabucasin overcomes cisplatin resistance in ovarian germ cell tumor-derived cell line by inhibiting cancer stemness

Yazar: Schmidtova, Silvia, Dorssers, Lambert C. J., Kalavska, Katarina, Gillis, Ad J. M., Oosterhuis, J. Wolter, Stoop, Hans, Miklikova, Svetlana, Kozovska, Zuzana, Burikova, Monika, Gercakova, Katarina, Durinikova, Erika, Chovanec, Michal, Mego, Michal, Kucerova, Lucia, Looijenga, Leendert H. J.
Yayımlandı Cancer Cell Int (2020)

Targeted serum miRNA (TSmiR) test for diagnosis and follow‐up of (testicular) germ cell cancer patients: A proof of principle

Yazar: Gillis, Ad J.M., Rijlaarsdam, Martin A., Eini, Ronak, Dorssers, Lambert C.J., Biermann, Katharina, Murray, Matthew J., Nicholson, James C., Coleman, Nicholas, Dieckmann, Klaus-Peter, Belge, Gazanfer, Bullerdiek, Jörn, Xu, Tom, Bernard, Nathalie, Looijenga, Leendert H.J.
Yayımlandı Mol Oncol (2013)

Serum microRNA profiles in athyroid patients on and off levothyroxine therapy

Yazar: Massolt, Elske T., Chaker, Layal, Visser, Theo J., Gillis, Ad J. M., Dorssers, Lambert C. J., Beukhof, Carolien M., Kam, Boen L. R., Franssen, Gaston J., Brigante, Giulia, van Ginhoven, Tessa M., Visser, W. Edward, Looijenga, Leendert H. J., Peeters, Robin P.
Yayımlandı PLoS One (2018)

Identification and Validation Model for Informative Liquid Biopsy-Based microRNA Biomarkers: Insights from Germ Cell Tumor In Vitro, In Vivo and Patient-Derived Data

Yazar: Lobo, João, Gillis, Ad J.M., van den Berg, Annette, Dorssers, Lambert C. J., Belge, Gafanzer, Dieckmann, Klaus-Peter, Roest, Henk P., van der Laan, Luc J. W., Gietema, Jourik, Hamilton, Robert J., Jerónimo, Carmen, Henrique, Rui, Salvatori, Daniela, Looijenga, Leendert H. J.
Yayımlandı Cells (2019)

Imprints and DPPA3 are bypassed during pluripotency- and differentiation-coupled methylation reprogramming in testicular germ cell tumors

Yazar: Killian, J. Keith, Dorssers, Lambert C.J., Trabert, Britton, Gillis, Ad J.M., Cook, Michael B., Wang, Yonghong, Waterfall, Joshua J., Stevenson, Holly, Smith, William I., Noyes, Natalia, Retnakumar, Parvathy, Stoop, J. Hans, Oosterhuis, J. Wolter, Meltzer, Paul S., McGlynn, Katherine A., Looijenga, Leendert H.J.
Yayımlandı Genome Res (2016)

Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas

Yazar: Basten, Sander G., Davis, Erica E., Gillis, Ad J. M., van Rooijen, Ellen, Stoop, Hans, Babala, Nikolina, Logister, Ive, Heath, Zachary G., Jonges, Trudy N., Katsanis, Nicholas, Voest, Emile E., van Eeden, Freek J., Medema, Rene H., Ketting, René F., Schulte-Merker, Stefan, Looijenga, Leendert H. J., Giles, Rachel H.
Baskı/Yayın Bilgisi 2013