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VASA mRNA (DDX4) detection is more specific than immunohistochemistry using poly- or monoclonal antibodies for germ cells in the male urogenital tract

VASA, also known as DDX4, is reported to be specifically expressed in cells belonging to the germ cell lineage, both in males and females. Therefore, it could be an informative protein biomarker to be applied on semen to differentiate between obstructive and nonobstructive azoospermia (OA and NOA, r...

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Dettagli Bibliografici
Pubblicato in:Medicine (Baltimore)
Autori principali: Boellaard, Willem P.A., Stoop, Hans, Gillis, Ad J.M., Oosterhuis, J. Wolter., Looijenga, Leendert H.J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer Health 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627816/
https://ncbi.nlm.nih.gov/pubmed/28746190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000007489
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