NANOG promoter methylation and expression correlation during normal and malignant human germ cell development

Testicular germ cell tumors are the most frequent malignant tumors in young Caucasian males, with increasing incidence. The actual model of tumorigenesis is based on the theory that a block in maturation of fetal germ cells lead to formation of the intratubular germ cell neoplasia unclassified. Earl...

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Main Authors: Nettersheim, Daniel, Bierman, Katharina, Gillis, Ad JM, Steger, Klaus, Looijenga, Leendert HJ, Schorle, Hubert
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2011
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052918/
https://ncbi.nlm.nih.gov/pubmed/20930529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.1.13433
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