NANOG promoter methylation and expression correlation during normal and malignant human germ cell development

Testicular germ cell tumors are the most frequent malignant tumors in young Caucasian males, with increasing incidence. The actual model of tumorigenesis is based on the theory that a block in maturation of fetal germ cells lead to formation of the intratubular germ cell neoplasia unclassified. Earl...

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Bibliographic Details
Main Authors: Nettersheim, Daniel, Bierman, Katharina, Gillis, Ad JM, Steger, Klaus, Looijenga, Leendert HJ, Schorle, Hubert
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052918/
https://ncbi.nlm.nih.gov/pubmed/20930529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.1.13433
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