DICER1 RNase IIIb domain mutations are infrequent in testicular germ cell tumours

BACKGROUND: Testicular Germ Cell Tumours (TGCT) are the most frequently occurring malignancy in males from 15–45 years of age. They are derived from germ cells unable to undergo physiological maturation, although the genetic basis for this is poorly understood. A recent report showed that mutations...

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Autores principales: de Boer, Carmela M, Eini, Ronak, Gillis, Ad M, Stoop, Hans, Looijenga, Leendert HJ, White, Stefan J
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Short Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503615/
https://ncbi.nlm.nih.gov/pubmed/23068969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-569
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