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DICER1 RNase IIIb domain mutations are infrequent in testicular germ cell tumours

BACKGROUND: Testicular Germ Cell Tumours (TGCT) are the most frequently occurring malignancy in males from 15–45 years of age. They are derived from germ cells unable to undergo physiological maturation, although the genetic basis for this is poorly understood. A recent report showed that mutations...

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Autors principals: de Boer, Carmela M, Eini, Ronak, Gillis, Ad M, Stoop, Hans, Looijenga, Leendert HJ, White, Stefan J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503615/
https://ncbi.nlm.nih.gov/pubmed/23068969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-569
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