XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality

Background: The event of X chromosome inactivation induced by XIST, which is physiologically observed in females, is retained in testicular germ cell tumors (TGCTs), as a result of a supernumerary X chromosome constitution. X chromosome inactivation also occurs in male germline, specifically during...

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Publicat a:Cancers (Basel)
Autors principals: Lobo, João, Nunes, Sandra P., Gillis, Ad J. M., Barros-Silva, Daniela, Miranda-Gonçalves, Vera, van den Berg, Annette, Cantante, Mariana, Guimarães, Rita, Henrique, Rui, Jerónimo, Carmen, Looijenga, Leendert H. J.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769809/
https://ncbi.nlm.nih.gov/pubmed/31533343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091385
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