Differential methylation EPIC analysis discloses cisplatin-resistance related hypermethylation and tumor-specific heterogeneity within matched primary and metastatic testicular germ cell tumor patient tissue samples

Testicular germ cell tumors (TGCTs) are among the most common solid malignancies in young-adult men, and currently most mortality is due to metastatic disease and emergence of resistance to cisplatin. There is some evidence that increased methylation is one mechanism behind this resistance, stemming...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Epigenetics
Päätekijät: Lobo, João, Constâncio, Vera, Leite-Silva, Pedro, Guimarães, Rita, Cantante, Mariana, Braga, Isaac, Maurício, Joaquina, Looijenga, Leendert H. J., Henrique, Rui, Jerónimo, Carmen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2021
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025580/
https://ncbi.nlm.nih.gov/pubmed/33823933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01048-y
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