Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors

Testicular germ cell tumors (TGCTs) are the most common cancers in men aged 15–39 years and are divided into two major groups, seminomas and nonseminomas. Novel treatment options are required for these patients, to limit side effects of chemotherapy. We hypothesized that promoter methylation of rele...

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Gepubliceerd in:Mol Oncol
Hoofdauteurs: Lobo, João, Constâncio, Vera, Guimarães‐Teixeira, Catarina, Leite‐Silva, Pedro, Miranda‐Gonçalves, Vera, Sequeira, José Pedro, Pistoni, Laura, Guimarães, Rita, Cantante, Mariana, Braga, Isaac, Maurício, Joaquina, Looijenga, Leendert H. J., Henrique, Rui, Jerónimo, Carmen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2021
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024740/
https://ncbi.nlm.nih.gov/pubmed/33513287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12909
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