Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors

Testicular germ cell tumors (TGCTs) are the most common cancers in men aged 15–39 years and are divided into two major groups, seminomas and nonseminomas. Novel treatment options are required for these patients, to limit side effects of chemotherapy. We hypothesized that promoter methylation of rele...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Lobo, João, Constâncio, Vera, Guimarães‐Teixeira, Catarina, Leite‐Silva, Pedro, Miranda‐Gonçalves, Vera, Sequeira, José Pedro, Pistoni, Laura, Guimarães, Rita, Cantante, Mariana, Braga, Isaac, Maurício, Joaquina, Looijenga, Leendert H. J., Henrique, Rui, Jerónimo, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024740/
https://ncbi.nlm.nih.gov/pubmed/33513287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12909
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