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Human Germ Cell Tumors are Developmental Cancers: Impact of Epigenetics on Pathobiology and Clinic

Current (high throughput omics-based) data support the model that human (malignant) germ cell tumors are not initiated by somatic mutations, but, instead through a defined locked epigenetic status, representative of their cell of origin. This elegantly explains the role of both genetic susceptibilit...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Lobo, João, Gillis, Ad J. M., Jerónimo, Carmen, Henrique, Rui, Looijenga, Leendert H. J.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359418/
https://ncbi.nlm.nih.gov/pubmed/30634670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20020258
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