Seminoma and Embryonal Carcinoma Footprints Identified by Analysis of Integrated Genome-Wide Epigenetic and Expression Profiles of Germ Cell Cancer Cell Lines

BACKGROUND: Originating from Primordial Germ Cells/gonocytes and developing via a precursor lesion called Carcinoma In Situ (CIS), Germ Cell Cancers (GCC) are the most common cancer in young men, subdivided in seminoma (SE) and non-seminoma (NS). During physiological germ cell formation/maturation,...

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Main Authors: van der Zwan, Yvonne G., Rijlaarsdam, Martin A., Rossello, Fernando J., Notini, Amanda J., de Boer, Suzan, Watkins, D. Neil, Gillis, Ad J. M., Dorssers, Lambert C. J., White, Stefan J., Looijenga, Leendert H. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041891/
https://ncbi.nlm.nih.gov/pubmed/24887064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098330
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