A Reliable Enantioselective Route to Mono-Protected N1-Cbz Piperazic Acid Building Block

por Papadaki, Evanthia, Georgiadis, Dimitris, Tsakos, Michail
Publicado no Molecules (2020)

The Discovery of Insulin-Regulated Aminopeptidase (IRAP) Inhibitors: A Literature Review

por Georgiadis, Dimitris, Ziotopoulou, Angeliki, Kaloumenou, Eleni, Lelis, Angelos, Papasava, Antonia
Publicado no Front Pharmacol (2020)

Critical role of inter-domain interactions on the conformational change and catalytic mechanism of Endoplasmic Reticulum Aminopeptidase 1

por Stamogiannos, Athanasios, Maben, Zachary, Papakyriakou, Athanasios, Mpakali, Anastasia, Kokkala, Paraskevi, Georgiadis, Dimitris, Stern, Lawrence J., Stratikos, Efstratios
Publicado no Biochemistry (2017)

Insights from Selective Non-phosphinic Inhibitors of MMP-12 Tailored to Fit with an S(1)′ Loop Canonical Conformation

por Devel, Laurent, Garcia, Sandra, Czarny, Bertrand, Beau, Fabrice, Lajeunesse, Evelyne, Vera, Laura, Georgiadis, Dimitris, Stura, Enrico, Dive, Vincent
Publicado em 2010

Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis

por Chen, Liye, Ridley, Anna, Hammitzsch, Ariane, Al-Mossawi, Mohammad Hussein, Bunting, Helen, Georgiadis, Dimitris, Chan, Antoni, Kollnberger, Simon, Bowness, Paul
Publicado no Ann Rheum Dis (2016)

Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1

por Giastas, Petros, Mpakali, Anastasia, Papakyriakou, Athanasios, Lelis, Aggelos, Kokkala, Paraskevi, Neu, Margarete, Rowland, Paul, Liddle, John, Georgiadis, Dimitris, Stratikos, Efstratios
Publicado no Proc Natl Acad Sci U S A (2019)

The N Domain of Human Angiotensin-I-converting Enzyme: THE ROLE OF N-GLYCOSYLATION AND THE CRYSTAL STRUCTURE IN COMPLEX WITH AN N DOMAIN-SPECIFIC PHOSPHINIC INHIBITOR, RXP407

por Anthony, Colin S., Corradi, Hazel R., Schwager, Sylva L. U., Redelinghuys, Pierre, Georgiadis, Dimitris, Dive, Vincent, Acharya, K. Ravi, Sturrock, Edward D.
Publicado em 2010

Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)

por Koumantou, Despoina, Barnea, Eilon, Martin-Esteban, Adrian, Maben, Zachary, Papakyriakou, Athanasios, Mpakali, Anastasia, Kokkala, Paraskevi, Pratsinis, Harris, Georgiadis, Dimitris, Stern, Lawrence J., Admon, Arie, Stratikos, Efstratios
Publicado no Cancer Immunol Immunother (2019)

Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses

por Zervoudi, Efthalia, Saridakis, Emmanuel, Birtley, James R., Seregin, Sergey S., Reeves, Emma, Kokkala, Paraskevi, Aldhamen, Yasser A., Amalfitano, Andrea, Mavridis, Irene M., James, Edward, Georgiadis, Dimitris, Stratikos, Efstratios
Publicado em 2013

A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by endoplasmic reticulum aminopeptidase 1

por Mavridis, George, Arya, Richa, Domnick, Alexander, Zoidakis, Jerome, Makridakis, Manousos, Vlahou, Antonia, Mpakali, Anastasia, Lelis, Angelos, Georgiadis, Dimitris, Tampé, Robert, Papakyriakou, Athanasios, Stern, Lawrence J., Stratikos, Efstratios
Publicado no J Biol Chem (2020)

Autoimmune Disease-Associated Variants of Extracellular Endoplasmic Reticulum Aminopeptidase 1 Induce Altered Innate Immune Responses by Human Immune Cells

por Aldhamen, Yasser A., Pepelyayeva, Yuliya, Rastall, David P.W., Seregin, Sergey S., Zervoudi, Efthalia, Koumantou, Despoina, Aylsworth, Charles F., Quiroga, Dionisia, Godbehere, Sarah, Georgiadis, Dimitris, Stratikos, Efstratios, Amalfitano, Andrea
Publicado no J Innate Immun (2015)

A common SNP in ER aminopeptidase 2 induces a specificity switch that leads to altered antigen processing

por Evnouchidou, Irini, Birtley, James, Seregin, Sergey, Papakyriakou, Athanasios, Zervoudi, Efthalia, Samiotaki, Martina, Panayotou, George, Giastas, Petros, Petrakis, Olivia, Georgiadis, Dimitris, Amalfitano, Andrea, Saridakis, Emmanuel, Mavridis, Irene M., Stratikos, Efstratios
Publicado em 2012

Optical imaging of MMP-12 active form in inflammation and aneurysm

por Razavian, Mahmoud, Bordenave, Thomas, Georgiadis, Dimitris, Beau, Fabrice, Zhang, Jiasheng, Golestani, Reza, Toczek, Jakub, Jung, Jae-Joon, Ye, Yunpeng, Kim, Hye-Yeong, Han, Jinah, Dive, Vincent, Devel, Laurent, Sadeghi, Mehran M.
Publicado no Sci Rep (2016)

Novel Matrix Metalloproteinase 12 selective radiotracers for vascular molecular imaging

por Toczek, Jakub, Bordenave, Thomas, Gona, Kiran, Kim, Hye-Yeong, Beau, Fabrice, Georgiadis, Dimitris, Correia, Isabelle, Ye, Yunpeng, Razavian, Mahmoud, Jung, Jae-Joon, Lequin, Olivier, Dive, Vincent, Sadeghi, Mehran M., Devel, Laurent
Publicado no J Med Chem (2019)

Synthesis, in vitro and in vivo evaluation of MMP-12 selective optical probes

por Bordenave, Thomas, Helle, Marion, Beau, Fabrice, Georgiadis, Dimitris, Tepshi, Livia, Bernes, Mylène, Ye, Yunpeng, Levenez, Laure, Poquet, Enora, Nozach, Hervé, Razavian, Mahmoud, Toczek, Jakub, Stura, Enrico A., Dive, Vincent, Sadeghi, Mehran M., Devel, Laurent
Publicado no Bioconjug Chem (2016)