Novel Matrix Metalloproteinase 12 selective radiotracers for vascular molecular imaging

Matrix metalloproteinase-12 (MMP-12) is highly upregulated in several inflammatory diseases, including abdominal aortic aneurysm (AAA). Here we report four novel (99m)Tc-labeled radiotracers derived from a highly selective competitive MMP-12 inhibitor. These tracers in their (99g)Tc version were ass...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Toczek, Jakub, Bordenave, Thomas, Gona, Kiran, Kim, Hye-Yeong, Beau, Fabrice, Georgiadis, Dimitris, Correia, Isabelle, Ye, Yunpeng, Razavian, Mahmoud, Jung, Jae-Joon, Lequin, Olivier, Dive, Vincent, Sadeghi, Mehran M., Devel, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054845/
https://ncbi.nlm.nih.gov/pubmed/31603669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b01186
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