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Optical imaging of MMP-12 active form in inflammation and aneurysm

Matrix metalloproteinase (MMP)-12 plays a key role in the development of aneurysm. Like other members of MMP family, MMP-12 is produced as a proenzyme, mainly by macrophages, and undergoes proteolytic activation to generate an active form. Accordingly, molecular imaging of the MMP-12 active form can...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Razavian, Mahmoud, Bordenave, Thomas, Georgiadis, Dimitris, Beau, Fabrice, Zhang, Jiasheng, Golestani, Reza, Toczek, Jakub, Jung, Jae-Joon, Ye, Yunpeng, Kim, Hye-Yeong, Han, Jinah, Dive, Vincent, Devel, Laurent, Sadeghi, Mehran M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137160/
https://ncbi.nlm.nih.gov/pubmed/27917892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38345
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