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Novel Arginine-containing Macrocyclic MMP Inhibitors: Synthesis, (99m)Tc-labeling, and Evaluation
Matrix metalloproteinases (MMPs) are involved in tissue remodeling. Accordingly, MMP inhibitors and related radiolabeled analogs are important tools for MMP-targeted imaging and therapy in a number of diseases. Herein, we report design, synthesis, and evaluation of a new Arginine-containing macrocyc...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6076275/ https://ncbi.nlm.nih.gov/pubmed/30076321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29941-2 |
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