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Matrix metalloproteinase inhibitor, doxycycline and progression of calcific aortic valve disease in hyperlipidemic mice

Calcific aortic valve disease (CAVD) is the most common cause of aortic stenosis. Currently, there is no non-invasive medical therapy for CAVD. Matrix metalloproteinases (MMPs) are upregulated in CAVD and play a role in its pathogenesis. Here, we evaluated the effect of doxycycline, a nonselective M...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Jung, Jae-Joon, Razavian, Mahmoud, Kim, Hye-Yeong, Ye, Yunpeng, Golestani, Reza, Toczek, Jakub, Zhang, Jiasheng, Sadeghi, Mehran M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020643/
https://ncbi.nlm.nih.gov/pubmed/27619752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32659
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