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Insights from Selective Non-phosphinic Inhibitors of MMP-12 Tailored to Fit with an S(1)′ Loop Canonical Conformation
After the disappointment of clinical trials with early broad spectrum synthetic inhibitors of matrix metalloproteinases (MMPs), the field is now resurging with a new focus on the development of selective inhibitors that fully discriminate between different members of the MMP family with several ther...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975213/ https://ncbi.nlm.nih.gov/pubmed/20817735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.139634 |
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