Insights from Selective Non-phosphinic Inhibitors of MMP-12 Tailored to Fit with an S(1)′ Loop Canonical Conformation

After the disappointment of clinical trials with early broad spectrum synthetic inhibitors of matrix metalloproteinases (MMPs), the field is now resurging with a new focus on the development of selective inhibitors that fully discriminate between different members of the MMP family with several ther...

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Detaylı Bibliyografya
Asıl Yazarlar: Devel, Laurent, Garcia, Sandra, Czarny, Bertrand, Beau, Fabrice, Lajeunesse, Evelyne, Vera, Laura, Georgiadis, Dimitris, Stura, Enrico, Dive, Vincent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Enzymology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975213/
https://ncbi.nlm.nih.gov/pubmed/20817735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.139634
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