A Reliable Enantioselective Route to Mono-Protected N1-Cbz Piperazic Acid Building Block

le Papadaki, Evanthia, Georgiadis, Dimitris, Tsakos, Michail
Foilsithe in Molecules (2020)

The Discovery of Insulin-Regulated Aminopeptidase (IRAP) Inhibitors: A Literature Review

le Georgiadis, Dimitris, Ziotopoulou, Angeliki, Kaloumenou, Eleni, Lelis, Angelos, Papasava, Antonia
Foilsithe in Front Pharmacol (2020)

Critical role of inter-domain interactions on the conformational change and catalytic mechanism of Endoplasmic Reticulum Aminopeptidase 1

le Stamogiannos, Athanasios, Maben, Zachary, Papakyriakou, Athanasios, Mpakali, Anastasia, Kokkala, Paraskevi, Georgiadis, Dimitris, Stern, Lawrence J., Stratikos, Efstratios
Foilsithe in Biochemistry (2017)

Insights from Selective Non-phosphinic Inhibitors of MMP-12 Tailored to Fit with an S(1)′ Loop Canonical Conformation

le Devel, Laurent, Garcia, Sandra, Czarny, Bertrand, Beau, Fabrice, Lajeunesse, Evelyne, Vera, Laura, Georgiadis, Dimitris, Stura, Enrico, Dive, Vincent
Foilsithe 2010

Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis

le Chen, Liye, Ridley, Anna, Hammitzsch, Ariane, Al-Mossawi, Mohammad Hussein, Bunting, Helen, Georgiadis, Dimitris, Chan, Antoni, Kollnberger, Simon, Bowness, Paul
Foilsithe in Ann Rheum Dis (2016)

Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1

le Giastas, Petros, Mpakali, Anastasia, Papakyriakou, Athanasios, Lelis, Aggelos, Kokkala, Paraskevi, Neu, Margarete, Rowland, Paul, Liddle, John, Georgiadis, Dimitris, Stratikos, Efstratios
Foilsithe in Proc Natl Acad Sci U S A (2019)

The N Domain of Human Angiotensin-I-converting Enzyme: THE ROLE OF N-GLYCOSYLATION AND THE CRYSTAL STRUCTURE IN COMPLEX WITH AN N DOMAIN-SPECIFIC PHOSPHINIC INHIBITOR, RXP407

le Anthony, Colin S., Corradi, Hazel R., Schwager, Sylva L. U., Redelinghuys, Pierre, Georgiadis, Dimitris, Dive, Vincent, Acharya, K. Ravi, Sturrock, Edward D.
Foilsithe 2010

Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)

le Koumantou, Despoina, Barnea, Eilon, Martin-Esteban, Adrian, Maben, Zachary, Papakyriakou, Athanasios, Mpakali, Anastasia, Kokkala, Paraskevi, Pratsinis, Harris, Georgiadis, Dimitris, Stern, Lawrence J., Admon, Arie, Stratikos, Efstratios
Foilsithe in Cancer Immunol Immunother (2019)

Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses

le Zervoudi, Efthalia, Saridakis, Emmanuel, Birtley, James R., Seregin, Sergey S., Reeves, Emma, Kokkala, Paraskevi, Aldhamen, Yasser A., Amalfitano, Andrea, Mavridis, Irene M., James, Edward, Georgiadis, Dimitris, Stratikos, Efstratios
Foilsithe 2013

A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by endoplasmic reticulum aminopeptidase 1

le Mavridis, George, Arya, Richa, Domnick, Alexander, Zoidakis, Jerome, Makridakis, Manousos, Vlahou, Antonia, Mpakali, Anastasia, Lelis, Angelos, Georgiadis, Dimitris, Tampé, Robert, Papakyriakou, Athanasios, Stern, Lawrence J., Stratikos, Efstratios
Foilsithe in J Biol Chem (2020)

Autoimmune Disease-Associated Variants of Extracellular Endoplasmic Reticulum Aminopeptidase 1 Induce Altered Innate Immune Responses by Human Immune Cells

le Aldhamen, Yasser A., Pepelyayeva, Yuliya, Rastall, David P.W., Seregin, Sergey S., Zervoudi, Efthalia, Koumantou, Despoina, Aylsworth, Charles F., Quiroga, Dionisia, Godbehere, Sarah, Georgiadis, Dimitris, Stratikos, Efstratios, Amalfitano, Andrea
Foilsithe in J Innate Immun (2015)

A common SNP in ER aminopeptidase 2 induces a specificity switch that leads to altered antigen processing

le Evnouchidou, Irini, Birtley, James, Seregin, Sergey, Papakyriakou, Athanasios, Zervoudi, Efthalia, Samiotaki, Martina, Panayotou, George, Giastas, Petros, Petrakis, Olivia, Georgiadis, Dimitris, Amalfitano, Andrea, Saridakis, Emmanuel, Mavridis, Irene M., Stratikos, Efstratios
Foilsithe 2012

Optical imaging of MMP-12 active form in inflammation and aneurysm

le Razavian, Mahmoud, Bordenave, Thomas, Georgiadis, Dimitris, Beau, Fabrice, Zhang, Jiasheng, Golestani, Reza, Toczek, Jakub, Jung, Jae-Joon, Ye, Yunpeng, Kim, Hye-Yeong, Han, Jinah, Dive, Vincent, Devel, Laurent, Sadeghi, Mehran M.
Foilsithe in Sci Rep (2016)

Novel Matrix Metalloproteinase 12 selective radiotracers for vascular molecular imaging

le Toczek, Jakub, Bordenave, Thomas, Gona, Kiran, Kim, Hye-Yeong, Beau, Fabrice, Georgiadis, Dimitris, Correia, Isabelle, Ye, Yunpeng, Razavian, Mahmoud, Jung, Jae-Joon, Lequin, Olivier, Dive, Vincent, Sadeghi, Mehran M., Devel, Laurent
Foilsithe in J Med Chem (2019)

Synthesis, in vitro and in vivo evaluation of MMP-12 selective optical probes

le Bordenave, Thomas, Helle, Marion, Beau, Fabrice, Georgiadis, Dimitris, Tepshi, Livia, Bernes, Mylène, Ye, Yunpeng, Levenez, Laure, Poquet, Enora, Nozach, Hervé, Razavian, Mahmoud, Toczek, Jakub, Stura, Enrico A., Dive, Vincent, Sadeghi, Mehran M., Devel, Laurent
Foilsithe in Bioconjug Chem (2016)