Therapeutic Targeting of Pancreatic Cancer via EphA2 Dimeric Agonistic Agents

بواسطة Salem, Ahmed F., Gambini, Luca, Udompholkul, Parima, Baggio, Carlo, Pellecchia, Maurizio
الحاوية / القاعدة Pharmaceuticals (Basel) (2020)

Stability and cell permeability of sulfonyl fluorides in the design of Lys-covalent antagonists of protein-protein interactions

بواسطة Gambini, Luca, Udompholkul, Parima, Salem, Ahmed F., Baggio, Carlo, Pellecchia, Maurizio
الحاوية / القاعدة ChemMedChem (2020)

Potential Therapeutic Targeting of Coronavirus Spike Glycoprotein Priming

بواسطة Barile, Elisa, Baggio, Carlo, Gambini, Luca, Shiryaev, Sergey A., Strongin, Alex Y., Pellecchia, Maurizio
الحاوية / القاعدة Molecules (2020)

Effective Tumor Targeting by EphA2-Agonist-Biotin-Streptavidin Conjugates

بواسطة Udompholkul, Parima, Baggio, Carlo, Gambini, Luca, Sun, Yu, Zhao, Ming, Hoffman, Robert M., Pellecchia, Maurizio
الحاوية / القاعدة Molecules (2021)

Covalent Inhibitors of Protein-Protein Interactions Targeting Lysine, Tyrosine, or Histidine Residues

بواسطة Gambini, Luca, Baggio, Carlo, Udompholkul, Parima, Jossart, Jennifer, Salem, Ahmed F., Perry, J. Jefferson P., Pellecchia, Maurizio
الحاوية / القاعدة J Med Chem (2019)

Aryl-fluorosulfate-based Lysine Covalent pan-Inhibitors of Apoptosis Proteins (IAP) Antagonists with Cellular Efficacy

بواسطة Baggio, Carlo, Udompholkul, Parima, Gambini, Luca, Salem, Ahmed F., Jossart, Jennifer, Perry, J. Jefferson P., Pellecchia, Maurizio
الحاوية / القاعدة J Med Chem (2019)

N-locking stabilization of covalent helical peptides: Application to Bfl-1 antagonists

بواسطة Baggio, Carlo, Udompholkul, Parima, Gambini, Luca, Jossart, Jennifer, Salem, Ahmed F., Håkansson, Maria, Perry, J. Jefferson P., Pellecchia, Maurizio
الحاوية / القاعدة Chem Biol Drug Des (2020)

Design of Potent pan-IAP and Lys-Covalent XIAP selective Inhibitors Using a Thermodynamics Driven Approach

بواسطة Baggio, Carlo, Gambini, Luca, Udompholkul, Parima, Salem, Ahmed F., Aronson, Alexander, Dona, Ada, Troadec, Estelle, Pichiorri, Flavia, Pellecchia, Maurizio
الحاوية / القاعدة J Med Chem (2018)

Structure-Based Design of Novel EphA2 Agonistic Agents with Nanomolar Affinity in Vitro and in Cell

بواسطة Gambini, Luca, Salem, Ahmed F., Udompholkul, Parima, Tan, Xiao-Feng, Baggio, Carlo, Shah, Neh, Aronson, Alexander, Song, Jikui, Pellecchia, Maurizio
الحاوية / القاعدة ACS Chem Biol (2018)

Prostate Cancer Metastases Are Strongly Inhibited by Agonistic Epha2 Ligands in an Orthotopic Mouse Model

بواسطة Salem, Ahmed F., Gambini, Luca, Billet, Sandrine, Sun, Yu, Oshiro, Hiromichi, Zhao, Ming, Hoffman, Robert M., Bhowmick, Neil A., Pellecchia, Maurizio
الحاوية / القاعدة Cancers (Basel) (2020)

Human resistin protects against endotoxic shock by blocking LPS–TLR4 interaction

بواسطة Jang, Jessica C., Li, Jiang, Gambini, Luca, Batugedara, Hashini M., Sati, Sandeep, Lazar, Mitchell A., Fan, Li, Pellecchia, Maurizio, Nair, Meera G.
الحاوية / القاعدة Proc Natl Acad Sci U S A (2017)

Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region

بواسطة Gambini, Luca, Rizzi, Luca, Pedretti, Alessandro, Taglialatela-Scafati, Orazio, Carucci, Mario, Pancotti, Andrea, Galli, Corinna, Read, Martin, Giurisato, Emanuele, Romeo, Sergio, Russo, Ilaria
الحاوية / القاعدة PLoS One (2015)

Correction: Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region

بواسطة Gambini, Luca, Rizzi, Luca, Pedretti, Alessandro, Taglialatela-Scafati, Orazio, Carucci, Mario, Pancotti, Andrea, Galli, Corinna, Read, Martin, Giurisato, Emanuele, Romeo, Sergio, Russo, Ilaria
الحاوية / القاعدة PLoS One (2016)

NMR Fingerprints of the Drug-like Natural-Product Space Identify Iotrochotazine A: A Chemical Probe to Study Parkinson’s Disease**

بواسطة Grkovic, Tanja, Pouwer, Rebecca H, Vial, Marie-Laure, Gambini, Luca, Noël, Alba, Hooper, John N A, Wood, Stephen A, Mellick, George D, Quinn, Ronald J
الحاوية / القاعدة Angew Chem Int Ed Engl (2014)

hBfl-1/hNOXA Interaction Studies Provide New Insights on the Role of Bfl-1 in Cancer Cell Resistance and for the Design of Novel Anticancer Agents

بواسطة Barile, Elisa, Marconi, Guya D., De, Surya K., Baggio, Carlo, Gambini, Luca, Salem, Ahmed F., Kashyap, Manoj K., Castro, Januario E., Kipps, Thomas J., Pellecchia, Maurizio
الحاوية / القاعدة ACS Chem Biol (2016)

Reduction of Circulating Cancer Cells and Metastases in Breast-Cancer Models by a Potent EphA2-Agonistic Peptide–Drug Conjugate

بواسطة Salem, Ahmed F., Wang, Si, Billet, Sandrine, Chen, Jie-Fu, Udompholkul, Parima, Gambini, Luca, Baggio, Carlo, Tseng, Hsian-Rong, Posadas, Edwin M., Bhowmick, Neil A., Pellecchia, Maurizio
الحاوية / القاعدة J Med Chem (2018)